Born in New York de Picciotto attended Amherst College and the University of Pennsylvania Law School.
In 1983, de Picciotto co-founded Advantage International, which later became Octagon. Octagon is a the leader in sports marketing, talent representation. For three decades de Picciotto has helped build Octagon into the global leader in talent representation, property ownership, event management and sports and entertainment marketing. He has built and managed many recognizable names and companies world wide including Super Bowl Champions, Olympic gold medalists, and royalty.